Single-dose oral treatment of gonorrhea in men and women, using ampicillin alone and combined with probenecid.
نویسندگان
چکیده
منابع مشابه
Oral cefuroxime axetil compared with oral ampicillin in treating acute uncomplicated gonorrhoea.
The efficacy and tolerance of single oral doses of cefuroxime axetil (1.5 g) were compared with oral ampicillin (3 g) for treating acute gonococcal urethritis in 110 men and 30 women. Each dose was given with 1 g probenecid. Of the 62 assessable patients who received ampicillin, two failed to respond to treatment. Of 67 assessable patients who received cefuroxime axetil, one failed to respond. ...
متن کاملAdvantages of adding a course of tetracycline to single dose ampicillin and probenecid in the treatment of gonorrhoea.
Chlamydia trachomatis was reisolated from 11 of 12 men with gonorrhoea who had initially yielded chlamydiae and who had been treated with ampicillin and probenecid (AMP) only, but from none of five such men treated with ampicillin and probenecid followed by tetracycline (AMPT). These results correlated with the absence of postgonococcal urethritis (PGU) in the group treated with AMPT. C trachom...
متن کاملComparative trial of single-dose ciprofloxacin and ampicillin plus probenecid for treatment of gonococcal urethritis in men.
In a double-blind comparative trial, 100 men with uncomplicated gonorrhea caused by beta-lactamase-negative Neisseria gonorrhoeae were treated with a single 0.25-g dose of ciprofloxacin administered orally or with 3.5 g of ampicillin plus 1.0 g of probenecid administered orally. Urethral infection was eradicated in all 49 men treated with ciprofloxacin and in 47 (92%) of 51 men treated with amp...
متن کاملComparative therapeutic and pharmacological evaluation of amoxicillin and ampicillin plus probenecid for the treatment of gonorrhea.
Single doses of 3.5 g of ampicillin with 1.0 g of probenecid or of 3.0 g of amoxicillin alone were administered orally to 58 males and 56 females with uncomplicated gonococcal infection. The failure rate for genital or anal infection, or both, was 1.7% for ampicillin plus probenecid and 4.2% for amoxicillin alone. However, patients with oropharyngeal infection responded poorly. Seventy-five iso...
متن کاملSingle-dose oral ampicillin in the treatment of gonococcal urethritis in males.
Penicillin and its analogues have been, and still are, the drugs of choice in the treatment of gonorrhoea in most parts of the world. The United States Centre for Disease Control recommends, as first line single-dose treatment, the use of either aqueous procaine penicillin G (4.8 mega-units intramuscularly as a single-dose with oral probenecid 1 g by mouth) or ampicillin 3.5 g (or amoxycillin 3...
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عنوان ژورنال:
- The British journal of venereal diseases
دوره 47 6 شماره
صفحات -
تاریخ انتشار 1971